Can Google Sheets Open XLSX Files?
Compatibility information for .XLSX files in Google Sheets.
Recommended Method
Upload the .xlsx file to Google Drive and open it with Google Sheets. You can edit the Excel file in Sheets while keeping it in its original Microsoft Excel format, or convert a copy to Google Sheets when you need features that require the native Sheets format.
Compatibility Notes
Google officially supports opening and editing Microsoft Excel .xlsx files in Google Sheets and saving changes to the original Excel file. Conversion to Google Sheets is optional, but some Google Sheets-specific features require conversion. For complex workbooks, review important formulas, formatting and spreadsheet behavior after editing.